文部科学省 科学研究費補助金 学術変革領域研究 (A) 2023〜2027年度
FY2023-2027 MEXT KAKENHI Grant-in-Aid for Transformative Research Area (A)
Achievements
multimodal.ecm[at]gmail.com (Please replace [at] with @)
22) Deficiency of mastl, a mitotic regulator, results in cell detachment from developing tissues of zebrafish embryos
Utsumi H., Yabe T, Koshida S., Yamashita A., and Takada S.
Frontiers in Cell and Developmental Biology, 12:1375655 (2024)
21) Spatial cell fate manipulation of human pluripotent stem cells by controlling the microenvironment using photocurable hydrogel
Wang Z, Numada A, Wagai F, Oda Y, Ohgushi M, Maki K, Adachi T, and Eiraku M
20) Brain-derived endothelial cells are neuroprotective in a chronic cerebral hypoperfusion mouse model
Matsui Y, Muramatsu F, Nakamura H, Noda Y, Matsumoto K, Kishima H, and Takakura N
Communications Biology, 7, 338 (2024)
19) The humidity responsiveness of a poly(N-isopropylacrylamide) gel using a PEG/water mixed solution as the solvent
Makita R, Akimoto A, Enomoto T, Nishimoto T, Li X, Shibayama M, Yoshida R
18) Single-cell colocalization analysis using a deep generative model
Kojima Y, Mii S, Hayashi S, Hirose H, Ishikawa M, Akiyama M, Enomoto A, Shimamura T
17) Soluble Frizzled-related proteins promote exosome-mediated Wnt re-secretion.
Tran THN, Takada R, Elena Krayukhina E, Maruno T, Mii Y, Uchiyama S, and Takada S
Communications Biology, 7:254 (2024).
16) Dissection of N-deacetylase and N-sulfotransferase activities of NDST1 and their effects on Wnt8 distribution and signaling in Xenopus embryos
Suzuki M, Takada S, and Mii Y
Dev. Growth. Differ.,in press.
15) Surface Glycan Profiling of Extracellular Vesicles by Lectin Microarray and Glycoengineering for Control of Cellular Interactions
Shimoda A and Akiyoshi K
14) In vitro induction of patterned branchial arch-like aggregate from human pluripotent stem cells
Seto Y, Ogihara R, Takizawa K, and Eiraku M
13) Discovery of Transcription Factors Involved in the Maintenance of Resident Vascular Endothelial Stem Cell Properties
Konishi H, Rahmawati FN, Okamoto N, Akuta K, Inukai K, Jia W, Muramatsu F, and Takakura N
Molecular and Cellular Biology,44:17 (2023)
12) Aging impairs the ability of vascular endothelial stem cells to generate endothelial cells in mice
Shimizu S, Iba T, Naito H, Rahmawati FN, Konishi H, Jia W, Muramatsu F, and Takakura N
Angiogenesis,26:567-580 (2023).
11) Efficient selection of knocked-in pluripotent stem cells using a dual cassette cellular elimination system.
Nakade K, Tsukamoto S, Nakashima K, An Y, Sato I, Li J, Shimoda Y, Hemmi Y, Miwa Y, and Hayashi Y
Cell Rep. methods,3:100662 (2023)
10) Optogenetic control of gut movements reveals peristaltic wave-mediated induction of cloacal contractions and reactivation of impaired gut motility
Shikaya Y, Inaba M, Tadokoro R, Utsunomiya S, and Takahashi Y
Front. Physiol., Sec. Developmental Physiology, 14 (2023)
9) UNMF: a unified nonnegative matrix factorization for multi-dimensional omics data
Abe K and Shimamura T
Brief. Bioinform.,24:bbad253 (2023)
8) Topological data analysis of protein structure and inter/intra-molecular interaction changes attributable to amino acid mutations
Koseki J, Hayashi S, Kojima Y, Hirose H, and Shimamura T
Comput. Struct. Biotechnol. J.,21:2950 (2023).
7) Rapid and Highly Efficient Purification of Extracellular Vesicles Enabled by a TiO2 Hybridized Spongy-like Polymer
Kanao E, Ishida K, Mizuta R, Li Y, Imami K, Tanigawa T, Sasaki Y, Akiyoshi K, Adachi J, Otsuka K, Ishihama Y, and Kubo T*
Anal. Chem.,95, 38, 14502 (2023)
6) Simultaneous binding of bFGF to both FGFR and integrin maintains properties of primed human induced pluripotent stem cells
Cheng YS, Taniguchi Y, Yunoki Y, Masai S, Nogi M, Doi H, Sekiguchi K, and Nakagawa M
5) Visualization of basement membranes by a nidogen-based fluorescent reporter in mice
Futaki S, Horomoto A, Shimono C, Norioka N, Taniguchi Y, Hamaoka H, Kaneko M, Shigeta M, Abe T, Sekiguchi K, and Kondo Y
4) Gap junction-mediated contraction of myoepithelial cells induces the peristaltic transport of sweat in human eccrine glands
Nakashima K, Kato H, Kurata R, Luo Q, Hayakawa T, Okada F, Fujita F, Nakagawa Y, Tanemura A, Murota H, Katayama I, and Sekiguchi K
3) Laminin fragments conjugated with perlecan’s growth factor-binding domain differentiate human induced pluripotent stem cells into skin-derived precursor cells
Sugiyama‐Nakagiri Y, Yamashita S, Taniguchi Y, Shimono C, and Sekiguchi K
2) Polydom/SVEP1 binds to Tie1 and promotes migration of lymphatic endothelial cells
Sato-Nishiuchi R, Doiguchi M, Morooka N, and Sekiguchi K
J. Cell Biol., 222:e202208047 (2023).
1) Development of a method for isolating brain capillaries from a single neonatal mouse brain and comparison of proteomic profiles between neonatal and adult brain capillaries
Hamada Y, Ogata S, Masuda T, Ito S, and Ohtsuki S
Fluids Barriers CNS, 20:50 (2023).