Event   2025.05.15

マルチモダルECM数理科学x生命科学連携探索セミナー & UBI 合同セミナーを開催します．

We will hold the Joint Seminar on Multimodal ECM Mathematical Science × Life Science Collaboration Exploration and UBI Seminar.

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 Paper   2025.03.13

石原 (誠) (公募班A01)が，がんの悪化には「硬さ」が重要であることを発見し，iScienceに論文を発表しました．

Dr. Seiichiro Ishihara (A01) discovered that “stiffness” plays a crucial role in cancer progression and published a paper in iScience.

"Stiff extracellular matrix activates the transcription factor ATF5 to promote the proliferation of cancer cells"

Press release

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 Book   2025.03.04

領域名が特集タイトルになった月刊「細胞」2025年3月号 「細胞外情報を統御するマルチモーダルECM」が発売されました．

領域メンバーが多数執筆しています．

The March 2025 issue of the monthly journal Saibou, featuring the research domain as its special title, “Multimodal ECM Regulating Extracellular Information,” has been released. Many members of the research area have contributed to this issue.

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 Event   2025.09.03-04

International Symposium on Multimodal ECM -Toward Elucidating ECM Dynamics- を開催します．

We will hold the International Symposium on Multimodal ECM - Toward Elucidating ECM Dynamics-.

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 Paper   2025.02.25

佐藤 (公募班A01)が表皮細胞が作る真皮I型コラーゲンに関する論文をNature Communicationsに発表しました．

Dr. Sato (A01) has published a paper on dermal type I collagen produced by epidermal cells in Nature Communications.

"Keratinocyte-driven dermal collagen formation in the axolotl skin"

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 News   2025.02.19

領域内でのGel x Bio Fusionの取り組みをスタートしました．高分子材料工学と生物学の融合をより一層強化していきます．

We have launched initiatives for Gel x Bio Fusion within the region. We will further strengthen the integration of polymer materials engineering and biology.

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 News   2025.01.29

第1回マルチモーダルECM Fusion Workshopを1月29日に開催しました．

We hold the 1st Multimodal ECM Fusion Workshop on January 29th.  

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 Paper   2024.12.23

藤原 (領域代表, A01-1代表)が基底膜ライブイメージングと毛包発生に関する論文をJournal of Cell Biologyに発表しました．

プレスリリース

Dr. Fujiwara (Area Leader, A01-1) has published a paper on live imaging of basement membranes and hair follicle development in Journal of Cell Biology.

"An eGFP-Col4a2 mouse model reveals basement membrane dynamics underlying hair follicle morphogenesis"

Press release

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 News   2024.12.13

第47回日本分子生物学会年会 (11/27-29) にて領域共催シンポジウムを開催しました．

The symposium was held at the 47th Annual Meeting of the Molecular Biology Society of Japan (November 27-29, 2024).

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第97回日本生化学学会大会 (11/6-8) にて領域共催シンポジウムを開催しました．

The symposium was held at the 97th Annual Meeting of the Japanese Biochemical Society (November 6-8, 2024).

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Eventsページを更新しました．

"Events" page is now updated.

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 Paper   2024.12.06

大槻 (A03-2代表) らの論文がMatrix Biologyに掲載されました．

A paper by Dr. Ohtsuki (A03-2) et al. has been published.

"Fibrillin-1 G234D mutation in the hybrid1 domain causes tight skin associated with dysregulated elastogenesis and increased collagen cross-linking in mice" ​

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 Paper   2024.10.08

奥田 (公募班A01)，藤原 (領域代表, A01-1代表) らの共著論文がActa Biomaterialiaに掲載されました．

A co-authored paper by Dr. Okuda (A01) and Dr. Fujiwara (Area Leadrer, A01-1), et al. has been published in Acta Biomaterialia.

"Ex vivo SIM-AFM measurements reveal the spatial correlation of stiffness and molecular distributions in 3D living tissue" 

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 Paper   2024.09.18

藤原 (領域代表, A01-1代表)が毛包形成におけるCell-ECM interactionのダイナミクスについて論じた総説をDevelopmental Biologyに発表しました．

Dr. Fujiwara (Area Leader, A01-1) published a review article discussing the dynamics of cell-ECM interaction in hair follicle formation in Developmental Biology.

"Dynamic duo: Cell–extracellular matrix interactions in hair follicle development and regeneration"​​​